Busulfan



  • Manufactured by:
  • Contains / Salt: Busulfan


Busulfan Information



Busulfan Benefits & Uses

Busulfan is used to treat the following -

Busulfan Dosage & How to Take

This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.

Find the right dosage based on disease and age

Age Group Dosage
Adult
  • Disease: Chronic Myelogenous Leukemia (CML)
  • Before or After Meal: As advised by a physician
  • Single Maximum Dose: 0.8 mg/kg
  • Dosage Route: Parenteral
  • Frequency: 6 hourly
  • Course Duration: 4 days
  • Special Instructions: As prescribed by the doctor
Geriatric
  • Disease: Chronic Myelogenous Leukemia (CML)
  • Before or After Meal: As advised by a physician
  • Single Maximum Dose: 0.8 mg/kg
  • Dosage Route: Parenteral
  • Frequency: 6 hourly
  • Course Duration: 4 days
  • Special Instructions: As prescribed by the doctor


Busulfan Side Effects

Based on research, the following side effects have been observed when Busulfan is used -

Moderate

Mild

Busulfan Related Warnings

  • Is the use of Busulfan safe for pregnant women?


    Busulfan shows severe side effect on pregnant women. For this reason, pregnant women should only take it after taking medical advice.

    Severe
  • Is the use of Busulfan safe during breastfeeding?


    Women who are breastfeeding, may experience serious side effects after taking Busulfan. So it is adviced to consult the doctor before using it.

    Severe
  • What is the effect of Busulfan on the Kidneys?


    There are no side effects of Busulfan on the kidneys.

    Safe
  • What is the effect of Busulfan on the Liver?


    Very few cases of side effects of Busulfan on the liver have been reported.

    Mild
  • What is the effect of Busulfan on the Heart?


    Very few cases of side effects of Busulfan on the heart have been reported.

    Mild


Severe Interaction of Busulfan with Other Drugs

Busulfan should not be taken with following medicines due to severe side effects it may cause to patients -

Severe

Moderate



Busulfan Contraindications

If you are suffering from any of the following diseases, you should not take Busulfan unless your doctor advises you to do so -



Frequently asked Questions about Busulfan

  • Is this Busulfan habit forming or addictive?


    Busulfan is not addictive in nature.

    No
  • Is it safe to drive or operate heavy machinery when consuming?


    No, you should not drive or operate heavy machinery after taking Busulfan as you may feel sleepy.

    Dangerous
  • Is it safe?


    Yes, but take Busulfan only as per medical advice.

    Safe, but take only on Doctor's advise
  • Is it able to treat mental disorders?


    No, the use of Busulfan in mental disorders is not effective.

    No

Busulfan Interactions with Food and Alcohol

  • Interaction between Food and Busulfan


    You can take Busulfan with food.

    Safe
  • Interaction between Alcohol and Busulfan


    Information about the interaction of Busulfan and alcohol is not currently available because this topic has not been researched yet.

    Unknown


See all substitutes for Busulfan


This medicine data has been created by -

Vikas Chauhan

B.Pharma, Pharmacy
5 Years of Experience


References

April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 258-260

KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 861

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Busulfex (busulfan)

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Myleran® (busulfan)



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