Primidone

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Primidone Information



Primidone Benefits & Uses

Primidone is used to treat the following -

Main Benefits

Primidone Dosage & How to Take

This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.

Find the right dosage based on disease and age

Age Group Dosage
Adult
  • Disease: Epilepsy
  • Before or After Meal: Either
  • Single Maximum Dose: 250 mg
  • Dosage Form: Tablet
  • Dosage Route: Oral
  • Frequency: 3 daily
  • Course Duration: As directed by the doctor
  • Special Instructions: Dosage range: 750 - 2000 mg/day as needed
Geriatric
  • Disease: Epilepsy
  • Before or After Meal: Either
  • Single Maximum Dose: 250 mg
  • Dosage Form: Tablet
  • Dosage Route: Oral
  • Frequency: 3 daily
  • Course Duration: As directed by the doctor
  • Special Instructions: Dosage range: 750 - 2000 mg/day as needed
13 - 18 years (Adolescent)
  • Disease: Epilepsy
  • Before or After Meal: Either
  • Single Maximum Dose: 250 mg
  • Dosage Form: Tablet
  • Dosage Route: Oral
  • Frequency: 3 daily
  • Course Duration: As directed by the doctor
  • Special Instructions: Dosage range: 750 - 2000 mg/day as needed
2 - 12 years (Child)
  • Disease: Epilepsy
  • Before or After Meal: Either
  • Single Maximum Dose: 25 mg/kg
  • Dosage Form: Tablet
  • Dosage Route: Oral
  • Frequency: 1 daily
  • Course Duration: As directed by the doctor
  • Special Instructions: dose may increase 1000 mg/day as needed, children age less than 8 years
Infant (1 month to 2 years)
  • Disease: Epilepsy
  • Before or After Meal: Either
  • Single Maximum Dose: 25 mg/kg
  • Dosage Form: Tablet
  • Dosage Route: Oral
  • Frequency: 1 daily
  • Course Duration: As directed by the doctor
  • Special Instructions: dose may increase 1000 mg/day as needed
Neonates (0 to 1 month)
  • Disease: Epilepsy
  • Before or After Meal: Either
  • Single Maximum Dose: 20 mg/kg
  • Dosage Form: Tablet
  • Dosage Route: Oral
  • Frequency: 1 daily
  • Course Duration: As directed by the doctor
  • Special Instructions: dose may increase 1000 mg/day as needed


Primidone Side Effects

Based on research, the following side effects have been observed when Primidone is used -

Common

  • Drowsiness
  • Nausea or vomiting
  • Unsteadiness
  • Dizziness

Primidone Related Warnings

  • Is the use of Primidone safe for pregnant women?


    Primidone can cause unwanted side effects in pregnant women. If you experience any side effects, stop taking Primidone right away. Take your doctor's advice before taking it again.

    Moderate
  • Is the use of Primidone safe during breastfeeding?


    Primidone should not be taken without taking your doctor's advice, as it may have severe side effects on breastfeeding women.

    Severe
  • What is the effect of Primidone on the Kidneys?


    Primidone rarely affects the kidneys.

    Mild
  • What is the effect of Primidone on the Liver?


    Primidone has very mild side effects on the liver.

    Mild
  • What is the effect of Primidone on the Heart?


    Using Primidone does not have any harmful effects on the heart.

    Safe


Severe Interaction of Primidone with Other Drugs

Primidone should not be taken with following medicines due to severe side effects it may cause to patients -

Moderate



Primidone Contraindications

If you are suffering from any of the following diseases, you should not take Primidone unless your doctor advises you to do so -



Frequently asked Questions about Primidone

  • Is this Primidone habit forming or addictive?


    Yes, Primidone can get addictive. Consume it only after doctor's advise.

    Yes
  • Is it safe to drive or operate heavy machinery when consuming?


    No, you should not drive or operate heavy machinery after taking Primidone as you may feel sleepy.

    Dangerous
  • Is it safe?


    Yes, but consume Primidone only on doctor's advice.

    Safe, but take only on Doctor's advise
  • Is it able to treat mental disorders?


    Primidone has been seen to have positive effect on patients with mental disorders.

    Yes

Primidone Interactions with Food and Alcohol

  • Interaction between Food and Primidone


    Taking Primidone with food is safe.

    Safe
  • Interaction between Alcohol and Primidone


    Taking alcohol with Primidone can be dangerous.

    Severe


See all substitutes for Primidone


This medicine data has been created by -

Vikas Chauhan

B.Pharma, Pharmacy
5 Years of Experience


References

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Mysoline® (primidone)

KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 413



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