Periset Injection

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Periset Injection Information

Periset Injection, a prescription drug, is manufactured in various forms such as Injection. Primarily, it is used for the treatment of Nausea and Vomiting.

The optimal dosage of Periset Injection is largely dependent on the individual's body weight, medical history, gender and age. The condition it has been prescribed for, and the route of administration also determine the right dosage. Refer to the dosage section for a detailed discussion.

Besides the aforementioned side effects, there are other adverse effects of Periset Injection as well, which are listed below. Such side effects of Periset Injection normally do not last long and go away once the treatment is completed. Consult your doctor if these side effects become worse or stay for a longer duration.

Furthermore, you should know that effect of Periset Injection is Safe for pregnant women and Mild for women who are breastfeeding. Further, the section on Periset Injection related warnings talks about Periset Injection's effects on the liver, heart and kidney.

Periset Injection is not recommended if you suffer from certain medical conditions as it can have adverse effects. Heart Disease, Calcium Deficiency, Potassium Deficiency are examples of such conditions. Other contraindications of Periset Injection have been discussed in the sections ahead.

Drug reaction of Periset Injection with other medicines has been reported. Refer to the list below for further details.

In addition to these precautions, you may also note that Periset Injection is not safe while driving, and is is not addictive in nature.


Periset Injection Benefits & Uses

Periset Injection is used to treat the following -

Periset Injection Dosage & How to Take

This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.

Find the right dosage based on disease and age

Age Group Dosage
Adult
  • Disease: Nausea and Vomiting
  • Before or After Meal: As advised by a physician
  • Single Maximum Dose: 0.15 mg/kg
  • Dosage Route: Parenteral
  • Frequency: once only
  • Course Duration: As directed by the doctor
  • Special Instructions: Given 30 minutes prior to the initiation of emetogenic chemotherapy.
Geriatric
  • Disease: Nausea and Vomiting
  • Before or After Meal: As advised by a physician
  • Single Maximum Dose: 0.15 mg/kg
  • Dosage Route: Parenteral
  • Frequency: once only
  • Course Duration: As directed by the doctor
  • Special Instructions: Given 30 minutes prior to the initiation of emetogenic chemotherapy.
13 - 18 years (Adolescent)
  • Disease: Nausea and Vomiting
  • Before or After Meal: As advised by a physician
  • Single Maximum Dose: 0.15 mg/kg
  • Dosage Route: Parenteral
  • Frequency: once only
  • Course Duration: As directed by the doctor
  • Special Instructions: Given 30 minutes prior to the initiation of emetogenic chemotherapy.
2 - 12 years (Child)
  • Disease: Nausea and Vomiting
  • Before or After Meal: As advised by a physician
  • Single Maximum Dose: 0.15 mg/kg
  • Dosage Route: Parenteral
  • Frequency: once only
  • Course Duration: As directed by the doctor
  • Special Instructions: Given 30 minutes prior to the initiation of emetogenic chemotherapy.
Infant (1 month to 2 years)
  • Disease: Nausea and Vomiting
  • Before or After Meal: As advised by a physician
  • Single Maximum Dose: 0.15 mg/kg
  • Dosage Route: Parenteral
  • Frequency: once only
  • Course Duration: As directed by the doctor
  • Special Instructions: Given 30 minutes prior to the initiation of emetogenic chemotherapy. Given dose older then 6 month

Periset Injection Side Effects

Based on research, the following side effects have been observed when Periset Injection is used -

Moderate

Mild

Periset Injection Related Warnings

  • Is the use of Periset Injection safe for pregnant women?


    Pregnant women can take Periset without worrying about any side effects.

    Safe
  • Is the use of Periset Injection safe during breastfeeding?


    Side effects of Periset on breastfeeding women are very mild.

    Mild
  • What is the effect of Periset Injection on the Kidneys?


    Using Periset does not have any harmful effects on kidneys.

    Safe
  • What is the effect of Periset Injection on the Liver?


    There may be an adverse effect on the liver after taking Periset. If you observe any side effects on your body then stop taking this drug. Take this medicine again only if your doctor advises you to do so.

    Moderate
  • What is the effect of Periset Injection on the Heart?


    Periset may cause harmful effects on the heart. if you feel it's having any such effect, then stop taking this drug, and restart only on your doctor's advice.

    Moderate

Severe Interaction of Periset Injection with Other Drugs

Periset Injection should not be taken with following medicines due to severe side effects it may cause to patients -

Severe

Moderate


Periset Injection Contraindications

If you are suffering from any of the following diseases, you should not take Periset Injection unless your doctor advises you to do so -


Frequently asked Questions about Periset Injection

  • Is this Periset Injection habit forming or addictive?


    No, there is no any evidence that Periset Injection is addictive.

    No
  • Is it safe to drive or operate heavy machinery when consuming?


    After taking Periset Injection, you should not drive or work on any heavy machine, as Periset Injection can make you drowsy.

    Dangerous
  • Is it safe?


    Periset Injection is safe but it is important to consult a doctor before taking it.

    Safe, but take only on Doctor's advise
  • Is it able to treat mental disorders?


    No, the use of Periset Injection in mental disorders is not effective.

    No

Periset Injection Interactions with Food and Alcohol

  • Interaction between Food and Periset Injection


    It is safe to take Periset Injection with food.

    Safe
  • Interaction between Alcohol and Periset Injection


    Consult your doctor before consuming alcohol while taking Periset Injection as it can have severe side effects.

    Severe

Frequently asked Questions about Periset Injection

Question about 6 years ago

How does Periset work?

Dr. Uday Nath Sahoo MBBS , Internal Medicine

Periset belongs to a class of compounds known as 5 -HT3 receptor antagonists. It blocks the action of serotonin completely at the 5-HT3 receptor sites present in our brain (vomiting centre) which provides relief to the patient from nausea and vomiting.

Question over 5 years ago

Does Periset cause headache?

Dr. MBBS , Pediatrics, Dermatology, General Physician, Dietician, Infectious Disease, Sexual Medicine & Marital Therapy, Obstetrics & Gynaecology, AIDS/HIV Sexually Transmitted Infections

Yes, headache is one of the common side effects of Periset. Apply balms and take a mild painkiller if a headache is of throbbing nature. Additionally, headaches can be prevented by doing yoga and meditation, by keeping away from electronic gadgets and computers, by eating light food and listening to relaxing music.

Question almost 6 years ago

How to take Periset?

Dr. Saurabh Shakya MBBS , General Physician

Periset is available in form of tablet, syrup, and injection. It should be taken as per your doctor's instructions. Ideally, Periset has to be taken with food to avoid stomach upset. The initial dose is usually taken half an hour before chemotherapy, 1 to 2 hours before radiation therapy and 1 hour before a surgery. Additional doses can be suggested by the doctor as per the individual requirements.

Question over 5 years ago

Can Periset be used for anxiety?

Dr. Piyush Malav MBBS, MS , General Surgery

Yes, Periset can be used for the symptom alleviation in anxiety, however, more clinical trials are needed to confirm this association. Anxiety can also be effectively managed by breathing deeply, practicing meditation, and not taking much stress. In case of severe anxiety please speak to your doctor.

Question almost 6 years ago

Is Periset an antibiotic?

Dr. Yogesh Kumar MBBS , General Physician

No, Periset is not an antibiotic. It is an anti-emetic medication which is used to prevent vomiting associated with chemotherapy and radiation therapy. 


See all substitutes for Periset


This medicine data has been created by -

Vikas Chauhan

B.Pharma, Pharmacy
5 Years of Experience


References

April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 947-948

KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 668

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Zofran (ondansetron hydrochloride)

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Zofran® (ondansetron hydrochloride)


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