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Mesopil is a prescription medicine that is available as a Tablet. Abortion are some of its major therapeutic uses. Other than this, Mesopil has some other therapeutic uses, which have been discussed ahead.
The right dosage of Mesopil depends on the age, gender, and medical history of the patient. The condition it has been prescribed for, and the route of administration also determine the right dosage. This information has been provided in detail in the dosage section.
Besides the aforementioned side effects, there are other adverse effects of Mesopil as well, which are listed below. Such side effects of Mesopil normally do not last long and go away once the treatment is completed. Consult your doctor if these side effects become worse or stay for a longer duration.
In addition, Mesopil's effect is Severe during pregnancy and Moderate for lactating mothers. It is important to know if Mesopil has any effect on the kidney, liver and heart. Information on such adverse effects, if any, has been given in the Mesopil related warnings section.
Other conditions have been mentioned below in the Mesopil contraindications section.
Additionally, Mesopil may also adversely react with other medicines. Refer to the list below for further details.
In addition to the above precautions for Mesopil, it is important to know that it is safe while driving, and is habit-forming.
Mesopil is used to treat the following -
Other Benefits
This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.
Find the right dosage based on disease and age
Age Group | Dosage |
Adult |
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Geriatric |
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Adult(Female) |
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Is the use of Mesopil safe for pregnant women?
Mesopil shows severe side effect on pregnant women. For this reason, pregnant women should only take it after taking medical advice.
Is the use of Mesopil safe during breastfeeding?
Mesopil may lead to some side effects in breastfeeding women. If you witness any unusal symptoms after taking Mesopil, discontinue its use and call your doctor right away. Follow your doctor's advice regarding the use of Mesopil.
What is the effect of Mesopil on the Kidneys?
Very few cases of side effects of Mesopil on kidney have been reported.
What is the effect of Mesopil on the Liver?
There may be an adverse effect on the liver after taking Mesopil. If you observe any side effects on your body then stop taking this drug. Take this medicine again only if your doctor advises you to do so.
What is the effect of Mesopil on the Heart?
The heart can be affected by Mesopil. If you experience any unwanted effects of this drug, stop taking it and consult your doctor. You should restart the medicine only after medical advice.
Mesopil should not be taken with following medicines due to severe side effects it may cause to patients -
Severe
Moderate
Mild
If you are suffering from any of the following diseases, you should not take Mesopil unless your doctor advises you to do so -
Is this Mesopil habit forming or addictive?
No, there is no any evidence that Mesopil is addictive.
Is it safe to drive or operate heavy machinery when consuming?
Yes, you can comfortably use machinery or drive after taking Mesopil since it will not make you feel sleepy.
Is it safe?
Mesopil should be used only after doctor's advice.
Is it able to treat mental disorders?
There is no benefit of taking Mesopil for mental disorders.
Interaction between Food and Mesopil
Due to a lack of research, nothing can be said about the consequences of taking Mesopil together with food.
Interaction between Alcohol and Mesopil
No research has been done on this till date. Therefore, it is not known what the effect of taking Mesopil with alcohol will be.
Yes, [Medcine] has been reported to cause uterine rupture when given only after the eighth week of pregnancy. This occurs in a few cases only. You are advised to report to your doctor immediately if you are experiencing heavy bleeding after taking Mesopil.
Take Mesopil as advised by your doctor. Do not discontinue the drug suddenly or take it longer than prescribed by your doctor.
Mesopil contains misoprostol which is a prostaglandin E1 (PGE1) analogue that possesses antisecretory property that inhibits gastric acid secretion. NSAIDs (nonsteroidal anti-inflammatory drugs) inhibits the synthesis of prostaglandins which leads to diminishing bicarbonate and mucus secretion which contributes to ulceration. Mesopil has mucosal protective properties that protect the stomach tissues from the damage caused by the stomach acid through decreased acid secretion and mucosal protective action. It induces labour by causing relaxation of cervix uteri (which is the lower part of the uterus). In the treatment of postpartum hemorrhage Mesopil works by causing contractions of smooth muscle fibres of the myometrium (middle layer of the uterine wall).
Yes, Mesopil is used to prevent and treat NSAIDs (nonsteroidal anti-inflammatory drugs) induced stomach ulcers. It works by inhibiting gastric acid secretion. NSAIDs (nonsteroidal anti-inflammatory drugs) inhibits the synthesis of prostaglandins which leads to diminishing bicarbonate and mucus (phlegm) secretion which contributes to ulceration. Mesopil has mucosal protective properties that protect the stomach tissues from the damage caused by the stomach acid through decreased acid secretion and mucosal protective action.
Yes, Mesopil causes bleeding this occurs due to the expelling the tissues of the fetus from the uterus. But if you observe that the heavy bleeding is continuing for more than 2 hours or usage of a sanitary napkin is more than 2 pads every hour, then this situation warrants immediate hospitalization to recover from blood loss. In case of incomplete or unsuccessful abortion, you may require surgical procedures. The heavy bleeding can be due to uterine rupture. However, this is a rare situation which occurs only in very few cases.
This medicine data has been created by -
B.Pharma, Pharmacy
5 Years of Experience
References
April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 867
KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 654
US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Cytotec® (misoprostol)