Mesopil

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Mesopil Information

Mesopil is a prescription medicine that is available as a Tablet. Abortion are some of its major therapeutic uses. Other than this, Mesopil has some other therapeutic uses, which have been discussed ahead.

The right dosage of Mesopil depends on the age, gender, and medical history of the patient. The condition it has been prescribed for, and the route of administration also determine the right dosage. This information has been provided in detail in the dosage section.

Besides the aforementioned side effects, there are other adverse effects of Mesopil as well, which are listed below. Such side effects of Mesopil normally do not last long and go away once the treatment is completed. Consult your doctor if these side effects become worse or stay for a longer duration.

In addition, Mesopil's effect is Severe during pregnancy and Moderate for lactating mothers. It is important to know if Mesopil has any effect on the kidney, liver and heart. Information on such adverse effects, if any, has been given in the Mesopil related warnings section.

Other conditions have been mentioned below in the Mesopil contraindications section.

Additionally, Mesopil may also adversely react with other medicines. Refer to the list below for further details.

In addition to the above precautions for Mesopil, it is important to know that it is safe while driving, and is habit-forming.



Mesopil Benefits & Uses

Mesopil is used to treat the following -

Other Benefits

Mesopil Dosage & How to Take

This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.

Find the right dosage based on disease and age

Age Group Dosage
Adult
  • Disease: Peptic Ulcer
  • Before or After Meal: With meal
  • Single Maximum Dose: 200 mcg
  • Dosage Form: Tablet
  • Dosage Route: Oral
  • Frequency: 4 daily
  • Course Duration: As directed by the doctor
  • Special Instructions: As prescribed by the doctor
Geriatric
  • Disease: Peptic Ulcer
  • Before or After Meal: With meal
  • Single Maximum Dose: 200 mcg
  • Dosage Form: Tablet
  • Dosage Route: Oral
  • Frequency: 4 hourly
  • Course Duration: As directed by the doctor
  • Special Instructions: As prescribed by the doctor
Adult(Female)
  • Disease: Post Delivery Bleeding
  • Before or After Meal: Either
  • Single Maximum Dose: 600 mcg
  • Dosage Form: Tablet
  • Dosage Route: Oral
  • Frequency: once only
  • Course Duration: As directed by the doctor
  • Special Instructions: As prescribed by the doctor

Mesopil Related Warnings

  • Is the use of Mesopil safe for pregnant women?


    Mesopil shows severe side effect on pregnant women. For this reason, pregnant women should only take it after taking medical advice.

    Severe
  • Is the use of Mesopil safe during breastfeeding?


    Mesopil may lead to some side effects in breastfeeding women. If you witness any unusal symptoms after taking Mesopil, discontinue its use and call your doctor right away. Follow your doctor's advice regarding the use of Mesopil.

    Moderate
  • What is the effect of Mesopil on the Kidneys?


    Very few cases of side effects of Mesopil on kidney have been reported.

    Mild
  • What is the effect of Mesopil on the Liver?


    There may be an adverse effect on the liver after taking Mesopil. If you observe any side effects on your body then stop taking this drug. Take this medicine again only if your doctor advises you to do so.

    Moderate
  • What is the effect of Mesopil on the Heart?


    The heart can be affected by Mesopil. If you experience any unwanted effects of this drug, stop taking it and consult your doctor. You should restart the medicine only after medical advice.

    Moderate


Severe Interaction of Mesopil with Other Drugs

Mesopil should not be taken with following medicines due to severe side effects it may cause to patients -

Severe

Moderate

Mild



Mesopil Contraindications

If you are suffering from any of the following diseases, you should not take Mesopil unless your doctor advises you to do so -



Frequently asked Questions about Mesopil

  • Is this Mesopil habit forming or addictive?


    No, there is no any evidence that Mesopil is addictive.

    No
  • Is it safe to drive or operate heavy machinery when consuming?


    Yes, you can comfortably use machinery or drive after taking Mesopil since it will not make you feel sleepy.

    Safe
  • Is it safe?


    Mesopil should be used only after doctor's advice.

    Safe, but take only on Doctor's advise
  • Is it able to treat mental disorders?


    There is no benefit of taking Mesopil for mental disorders.

    No

Mesopil Interactions with Food and Alcohol

  • Interaction between Food and Mesopil


    Due to a lack of research, nothing can be said about the consequences of taking Mesopil together with food.

    Unknown
  • Interaction between Alcohol and Mesopil


    No research has been done on this till date. Therefore, it is not known what the effect of taking Mesopil with alcohol will be.

    Unknown


Frequently asked Questions about Mesopil

Question about 4 years ago

Does Mesopil cause uterine rupture?

Dr. Joydeep Sarkar MBBS , Internal Medicine

Yes, [Medcine] has been reported to cause uterine rupture when given only after the eighth week of pregnancy. This occurs in a few cases only. You are advised to report to your doctor immediately if you are experiencing heavy bleeding after taking Mesopil.

Question about 5 years ago

How long can I safely take Mesopil?

Dr. Amit Singh MBBS , General Physician

Take Mesopil as advised by your doctor. Do not discontinue the drug suddenly or take it longer than prescribed by your doctor.

Question over 5 years ago

How does Mesopil work?

Dr. Suhas Bhargav MBBS , General Physician

Mesopil contains misoprostol which is a prostaglandin E1 (PGE1) analogue that possesses antisecretory property that inhibits gastric acid secretion. NSAIDs (nonsteroidal anti-inflammatory drugs) inhibits the synthesis of prostaglandins which leads to diminishing bicarbonate and mucus secretion which contributes to ulceration. Mesopil has mucosal protective properties that protect the stomach tissues from the damage caused by the stomach acid through decreased acid secretion and mucosal protective action. It induces labour by causing relaxation of cervix uteri (which is the lower part of the uterus). In the treatment of postpartum hemorrhage Mesopil works by causing contractions of smooth muscle fibres of the myometrium (middle layer of the uterine wall).

Question about 4 years ago

Is Mesopil used for ulcer?

Dr. Chinmaya Bal MBBS , General Physician

Yes, Mesopil is used to prevent and treat NSAIDs (nonsteroidal anti-inflammatory drugs) induced stomach ulcers. It works by inhibiting gastric acid secretion. NSAIDs (nonsteroidal anti-inflammatory drugs) inhibits the synthesis of prostaglandins which leads to diminishing bicarbonate and mucus (phlegm) secretion which contributes to ulceration. Mesopil has mucosal protective properties that protect the stomach tissues from the damage caused by the stomach acid through decreased acid secretion and mucosal protective action.

Question almost 5 years ago

Does Mesopil cause bleeding?

Dr. Uday Nath Sahoo MBBS , Internal Medicine

Yes, Mesopil causes bleeding this occurs due to the expelling the tissues of the fetus from the uterus. But if you observe that the heavy bleeding is continuing for more than 2 hours or usage of a sanitary napkin is more than 2 pads every hour, then this situation warrants immediate hospitalization to recover from blood loss. In case of incomplete or unsuccessful abortion, you may require surgical procedures. The heavy bleeding can be due to uterine rupture. However, this is a rare situation which occurs only in very few cases.



See all substitutes for Mesopil


This medicine data has been created by -

Vikas Chauhan

B.Pharma, Pharmacy
5 Years of Experience


References

April Hazard Vallerand, Cynthia A. Sanoski. [link]. Sixteenth Edition. Philadelphia, China: F. A. Davis Company; 2019: Page No 867

KD Tripathi. [link]. Seventh Edition. New Delhi, India: Jaypee Brothers Medical Publishers; 2013: Page No 654

US Food and Drug Administration (FDA) [Internet]. Maryland. USA; Package leaflet information for the user; Cytotec® (misoprostol)



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