Amisafe 250 Injection

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Amisafe 250 Injection Information

Amisafe 250 Injection is a commercial drug that is prescribed in the form of Injection. It is primarily used for the treatment of Urinary Tract Infection. Secondary and off-label uses of Amisafe 250 Injection have also been mentioned below.

The optimal dosage of Amisafe 250 Injection is largely dependent on the individual's body weight, medical history, gender and age. Individual symptoms and route of administration also determines the right dosage. Detailed information has been provided in the dosage section.

Some other side effects of Amisafe 250 Injection have been listed ahead. Such side effects of Amisafe 250 Injection normally do not last long and go away once the treatment is completed. If, however, they worsen or do not go away, please speak with your physician.

Furthermore, you should know that effect of Amisafe 250 Injection is Severe for pregnant women and Unknown for women who are breastfeeding. It is important to know if Amisafe 250 Injection has any effect on the kidney, liver and heart. Information on such adverse effects, if any, has been given in the Amisafe 250 Injection related warnings section.

Individuals suffering from medical conditions like Dehydration, Parkinson's Disease, Hearing Loss must refrain from the use of Amisafe 250 Injection since this can cause severe adverse effects. Some other conditions that can be affected by Amisafe 250 Injection are listed in the contraindications section below.

Drug interactions for Amisafe 250 Injection have been reported in the medical literature. A complete list of these interactions is given below.

In addition to the above precautions for Amisafe 250 Injection, it is important to know that it is safe while driving, and is habit-forming.


Amisafe 250 Injection Benefits & Uses

Amisafe 250 Injection is used to treat the following -

Main Benefits

Other Benefits

Amisafe 250 Injection Dosage & How to Take

This is the usual dosage recommended in most common treatment cases. Please remember that every patient and their case is different, so the dosage can be different based on the disease, route of administration, patient's age and medical history.

Find the right dosage based on disease and age

Age Group Dosage
Adult
  • Disease: Bacterial Infections
  • Before or After Meal: As advised by a physician
  • Single Maximum Dose: 7.5 mg/kg
  • Dosage Route: Parenteral
  • Frequency: doctor administered
  • Course Duration: As directed by the doctor
  • Special Instructions: As prescribed by the doctor
Geriatric
  • Disease: Bacterial Infections
  • Before or After Meal: Either
  • Single Maximum Dose: 7.5 mg/kg
  • Dosage Route: Parenteral
  • Frequency: 3 daily
  • Course Duration: 7 days
  • Special Instructions: As prescribed by the doctor
13 - 18 years (Adolescent)
  • Disease: Bacterial Infections
  • Before or After Meal: Either
  • Single Maximum Dose: 5 mg/kg
  • Dosage Route: Parenteral
  • Frequency: 3 daily
  • Course Duration: 7 days
  • Special Instructions: As prescribed by the doctor
Infant (1 month to 2 years)
  • Disease: Bacterial Infections
  • Before or After Meal: Either
  • Single Maximum Dose: 5 mg/kg
  • Dosage Route: Parenteral
  • Frequency: 3 daily
  • Course Duration: 7 days
  • Special Instructions: As prescribed by the doctor
Neonates (0 to 1 month)
  • Disease: Bacterial Infections
  • Before or After Meal: Either
  • Single Maximum Dose: 7.5 mg/kg
  • Dosage Route: Parenteral
  • Frequency: 3 daily
  • Course Duration: 7 days
  • Special Instructions: As prescribed by the doctor
2 - 12 years (Child)
  • Disease: Urinary Tract Infection (UTI)
  • Before or After Meal: As advised by a physician
  • Single Maximum Dose: 5 mg/kg
  • Dosage Route: Parenteral
  • Frequency: 3 daily
  • Course Duration: 10 days
  • Special Instructions: As prescribed by the doctor

Amisafe 250 Injection Side Effects

Based on research, the following side effects have been observed when Amisafe 250 Injection is used -

Moderate

Mild

Unknown

  • Uncoordinated Body Movements
  • Hearing Loss
  • Renal Impairment
  • Seizures (uncontrollable jerking of limbs)

Amisafe 250 Injection Related Warnings

  • Is the use of Amisafe 250 Injection safe for pregnant women?


    Amisafe has many dangerous side effects in pregnant women. If you are pregnant, do not consume Amisafe without medical advice.

    Severe
  • Is the use of Amisafe 250 Injection safe during breastfeeding?


    There is no research available on the side effects of Amisafe in breastfeeding women. Therefore, its impact is unknown.

    Unknown
  • What is the effect of Amisafe 250 Injection on the Kidneys?


    Amisafe may have severe effects on your kidney, so do not take it without consulting your doctor.

    Severe
  • What is the effect of Amisafe 250 Injection on the Liver?


    Side effects of Amisafe rarely affect the liver.

    Mild
  • What is the effect of Amisafe 250 Injection on the Heart?


    Very few cases of side effects of Amisafe on the heart have been reported.

    Mild

Severe Interaction of Amisafe 250 Injection with Other Drugs

Amisafe 250 Injection should not be taken with following medicines due to severe side effects it may cause to patients -

Severe


Amisafe 250 Injection Contraindications

If you are suffering from any of the following diseases, you should not take Amisafe 250 Injection unless your doctor advises you to do so -


Frequently asked Questions about Amisafe 250 Injection

  • Is this Amisafe 250 Injection habit forming or addictive?


    Forming a habit of Amisafe 250 Injection has not been reported.

    No
  • Is it safe to drive or operate heavy machinery when consuming?


    Yes, you can comfortably use machinery or drive after taking Amisafe 250 Injection since it will not make you feel sleepy.

    Safe
  • Is it safe?


    Yes, Amisafe 250 Injection is safe but you must consult your doctor before taking it.

    Safe, but take only on Doctor's advise
  • Is it able to treat mental disorders?


    No, Amisafe 250 Injection is not used to treat mental disorders.

    No

Amisafe 250 Injection Interactions with Food and Alcohol

  • Interaction between Food and Amisafe 250 Injection


    Taking Amisafe 250 Injection with food does not harm your health.

    Safe
  • Interaction between Alcohol and Amisafe 250 Injection


    No research has been done on this till date. Therefore, it is not known what the effect of taking Amisafe 250 Injection with alcohol will be.

    Unknown

Frequently asked Questions about Amisafe 250 Injection

Question over 5 years ago

Does Amisafe cover pseudomonas?

Dr. Sameer Awadhiya MBBS , Pediatrics

Yes, Amisafe is effective against bacteria (Pseudomonas). But it is also found that Pseudomonas can get resistant to this drug and in that case Amisafe will not produce desired results. If you are experiencing no symptomatic relief after taking this medicine then inform your doctor and follow his/her instructions.

Question over 5 years ago

Does Amisafe cause thrombocytopenia?

Dr. Gaurav MBBS , General Physician

Occasionally, Amisafe can cause drug-induced thrombocytopenia (blood clot formation in the vessel). However, if you experience severe thrombocytopenia after taking this medicine, please immediately seek medical help.

Question over 5 years ago

Can I take Amisafe with penicillin?

Dr. Braj Bhushan Ojha BAMS , Gastroenterology, Dermatology, Psychiatry, Ayurveda, Sexology, Diabetology

No, Amisafe cannot be taken with penicillin. Because penicillin inactivates the Amisafe by combining the beta-lactam ring of penicillin with an amino group of this drug to form amide which is biologically inactive. For this reason Amisafe should not be taken with penicillin. The chances of inactivation of this drug are higher in case of renal failure because in this case concentration of penicillin is higher in the kidney for a longer time as compared to the normal renal function. 

Question over 5 years ago

Is Amisafe ototoxic?

Dr. B. K. Agrawal MBBS, MD , Cardiology, General Physician, Internal Medicine

Yes, Amisafe has been reported to cause ototoxicity (hearing loss or deafness) which is irreversible and may progress after discontinuation of the drug. It is a common side effect of this medicine. If you experience hearing loss or deafness after consuming or applying for this medicine, then consult your doctor and follow his/her instructions.

Question about 6 years ago

How does Amisafe work?

Dr Anjum Mujawar MBBS, MBBS , Emergency Medicine

Amisafe is a broad-spectrum antibiotic which is active against both Gram-positive and Gram-negative bacteria. It works by preventing the synthesis of proteins that bacteria need to survive, in the absence of protein synthesis bacteria become vulnerable and dies. It is effective against different types of bacteria such as Escherichia coli, Proteus species, S. aureus, Acinetobacter and Serratia species.


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This medicine data has been created by -

Vikas Chauhan

B.Pharma, Pharmacy
5 Years of Experience

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